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| Similar words: Cerebellar Ataxia Cerebellar Diseases | |
| Hemangioblastoma Multiple Hemangioblastomas | Hemangioblastoma, Multiple | Hemangioblastomas | Hemangioblastomas, Multiple | Multiple Hemangioblastoma A benign tumor of the nervous system that may occur sporadically or in association with HIPPEL-LINDAU DISEASE. It accounts for approximately 2% of intracranial tumors, arising most frequently in the cerebellar hemispheres and vermis. Histologically, the tumors are composed of multiple capillary and sinusoidal channels lined with endothelial cells and clusters of lipid-laden pseudoxanthoma cells. Usually solitary, these tumors can be multiple and may also occur in the brain stem, spinal cord, retina, and supratentorial compartment. Cerebellar hemangioblastomas usually present in the third decade with INTRACRANIAL HYPERTENSION, and ataxia. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2071-2) | |
| Creutzfeldt-Jakob Syndrome CJD Variant (V-CJD) | New Variant Creutzfeldt-Jakob Disease | Spongiform Encephalopathy, Subacute | CJD | CJD (Creutzfeldt-Jakob Disease) | Creutzfeldt-Jakob Disease | Creutzfeldt-Jakob Disease, Familial | Familial Creutzfeldt-Jakob Disease A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27)) | |
| Medulloblastoma Arachnoidal Cerebellar Sarcoma, Circumscribed | Medulloblastoma, Desmoplastic | Medullomyoblastoma | Sarcoma, Cerebellar, Circumscribed Arachnoidal | Medulloblastoma, Adult | Medulloblastoma, Childhood | Melanocytic Medulloblastoma A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1) | |
| Tremor Action Tremor | Intention Tremor | Resting Tremor | Coarse Tremor | Continuous Tremor | Darkness Tremor | Fine Tremor | Intermittent Tremor | Involuntary Quiver | Massive Tremor | Passive Tremor | Persistent Tremor | Pill Rolling Tremor | Rest Tremor Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE. | |
| Hippel-Lindau Disease Cerebelloretinal Angiomatosis, Familial | Lindau Disease | von Hippel-Lindau Disease | Familial Cerebello-Retinal Angiomatosis | Lindau' | s Disease | von Hippel-Lindau Syndrome | Angiomatoses, Familial Cerebello-Retinal | Lindau' | s Diseases An autosomal dominant disorder associated with various neoplasms including central nervous system (most often cerebellar) and retinal HEMANGIOBLASTOMA, endolymphatic sac tumors, renal cell carcinoma (see CARCINOMA, RENAL CELL), renal and pancreatic cysts, HEMANGIOMA of the spinal cord, and PHEOCHROMOCYTOMA. The most common presenting manifestations are neurologic deficits associated with intracranial hemangioblastomas which may hemorrhage, causing ataxia, INTRACRANIAL HYPERTENSION, and other signs of neurologic dysfunction. (From Neurochirurgie 1998 Nov;44(4):258-66) | |
| Purkinje Cells Cells, Purkinje The output neurons of the cerebellar cortex. | |
| Lateral Medullary Syndrome Lateral Bulbar Syndrome | Posterior Inferior Cerebellar Artery Syndrome | Wallenberg Syndrome | Dorsolateral Medullary Syndrome | Vieseaux-Wallenberg Syndrome | Wallenberg' | s Syndrome | Lateral Medullary Syndromes | Syndrome, Wallenberg Infarction of the dorsolateral aspect of the medulla due to occlusion of the vertebral artery and/or the posterior inferior cerebellar artery. Clinical manifestations vary with the size of infarction, but may include loss of pain and temperature sensation in the ipsilateral face and contralateral body below the chin; ipsilateral HORNER SYNDROME; ipsilateral ATAXIA; DYSARTHRIA; VERTIGO; nausea, hiccup; dysphagia; and VOCAL CORD PARALYSIS. (From Adams et al., Principles of Neurology, 6th ed, p801) | |
| Disease Progression Disease Progressions | Progression, Disease | Progressions, Disease The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis. | |
| Histiocytic Necrotizing Lymphadenitis Kikuchi Disease | Lymphadenitis, Histiocytic Necrotizing | Kikuchi' | s Disease | Kikuchi-Fujimoto Disease | Disease, Kikuchi | Disease, Kikuchi' | s | Disease, Kikuchi-Fujimoto | Kikuchi Fujimoto Disease | Kikuchis Disease Development of lesions in the lymph node characterized by infiltration of the cortex or paracortex by large collections of proliferating histiocytes and complete or, more often, incomplete necrosis of lymphoid tissue. | |
| Cerebellar Cortex Cortex, Cerebellar The superficial gray matter of the cerebellum. It consists of two main layers, the stratum moleculare and the stratum granulosum. (Dorland, 28th ed) | |
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